UNIVERSITY OF CALIFORNIA, La Jolla, United States Read more
Prof. Guy BERTRAND
Guy Bertrand is Distinguished Professor and Director of the UCSD/CNRS Joint Research Chemistry Laboratory at the University of California at San Diego. He received his PhD from the University Paul Sabatier in 1979. After being a CNRS group leader at the University of Toulouse, and then at the Laboratoire de Chimie de Coordination du CNRS, he has been the Director of the Laboratoire d'Hétérochimie Fondamentale et Appliquée at the University Paul Sabatier from 1998 to 2005. From 2001 to 2012 he served as the Director of the UCR/CNRS Joint Research Chemistry Laboratory that he created, and moved to UC San Diego in 2012. For many years, challenging the rules in chemistry textbooks was one of his sources of inspiration, as exemplified by his quest for stable carbenes, nitrenes, diradicals, bent-allenes, etc. He still likes to tame reactive molecules, but he also wants to transform these compounds into useful tools for synthetic chemists. Recently, his group has shown that stable carbenes and related metal-free species can activate small molecules and stabilize highly reactive intermediates. Now, they wish to show that they are not only able to break bonds, but that they are also capable of transferring the corresponding fragments to substrates. In other words, they want their organic species to perform tasks that were previously exclusive for transition metal complexes.
Exploiting Conformational Control for Biomimetic Function and Reactivity
Prof. Jonathan CLAYDEN
UNIVERSITY OF BRISTOL, Bristol , United Kingdom Read more
Prof. Jonathan CLAYDEN
Jonathan Clayden was born in Uganda in 1968, grew up in the county of Essex in the East of England, and was an undergraduate at Churchill College, Cambridge. In 1992 he completed a PhD at the University of Cambridge with Dr Stuart Warren. After postdoctoral work at the École Normale Supérieure in Paris with Prof. Marc Julia, he moved in 1994 to the University of Manchester as a lecturer. In 2001 he was promoted to a professorship, in 2015 he moved to the University of Bristol. His research interests encompass various areas of synthesis and stereochemistry, particularly where conformation has a role to play: asymmetric synthesis, atropisomerism, organolithium chemistry, biomimetic function using dynamic foldamers, and using extended molecules to achieve long-range communication of information. He has published 250 papers, and is a co-author of the widely used undergraduate textbook on Organic Chemistry (2nd edn, 2012). His book “Organolithiums: Selectivity for Synthesis” was published in 2002. He was awarded the Royal Society of Chemistry’s Merck Award in 2011 and Tilden Prize in 2018, and he was awarded the Prix Franco-Britannique by the Société Française de Chimie in 2019. He has held a Royal Society Wolfson Research Merit award and a European Research Council Advanced Investigator Grant.
Symantec Programming of Chemistry
Prof. Leroy CRONIN
UNIVERSITY OF GLASGOW, Glasgow, United Kingdom Read more
Prof. Leroy CRONIN
Leroy (Lee) Cronin FRSE was born in the UK in 1973 was appointed to be Regius Professor of Chemistry in Glasgow in 2013 after being a professor (2009 & 2006) and reader in Glasgow since 2002. Between 2000-2002 he was a lecturer at the University of Birmingham. Alexander von Humboldt research fellow (Uni. of Bielefeld); 1997-1999: Research fellow (Uni. of Edinburgh); 1997: Ph.D. Bio-Inorganic Chemistry, Uni. of York; 1994 BSc. Chemistry, First Class, Uni. of York. Prizes include 2019 Japan Society of Coordination Chemistry International Prize, 2018 ACS Inorganic Lectureship, 2018 RSC Interdisciplinary Prize, 2015 RSC Tilden Prize, 2013 BP/RSE Hutton Prize, 2012 RSC Corday Morgan, 2011, Election to the Royal Society of Edinburgh in 2009. His research has four main aims 1) the construction of an artificial life form / work out how inorganic chemistry transitioned to biology / searching for new life forms; 2) the digitization of chemistry; and 3) the use of artificial intelligence in chemistry including the construction of ‘wet’ chemical computers; 4) The exploration of complexity and information in chemistry. He runs a team of around 60 people funded by grants from the UK EPSRC, US DARPA, Templeton, Google, BAe, JM and is developing both ‘open-source’ as well as commercial chemputers. See www.chemify.org
Discovering New Fluorination Reagents and Reactions by Probing the Unique Fluorine Effects
Prof. Jinbo HU
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, Shanghai, China
Rational Design of High-performance Mid-sized Catalysts Based on Acid–Base Combination Chemistry
Kazuaki Ishihara is a Professor in Graduate School of Engineering, Nagoya University, Japan. He received his Doctorate of Engineering degree from Nagoya University in 1991 with Professor Hisashi Yamamoto. After completing a postdoctoral fellowship at Harvard University with Professor E. J. Corey, he moved back to Japan in 1992 and worked his way up from Assistant Professor (1992–1997) to Associate Professor (1997–2002) and now his current position (2002–) at Nagoya University. Professor Ishihara has received numerous awards and honors for his work. His representative awards include: the Mukaiyama Award (2009), the Society of Iodine Science Award (2015), the Synthetic Organic Chemistry Award (2016), and the Chemical Society of Japan Award (2017). Professor Ishihara has served on numerous editorial advisory boards, including: “Letters in Organic Chemistry,” “European Journal of Organic Chemistry,” “Asian Journal of Organic Chemistry,” and “Topics in Current Chemistry.” His principle areas of research have evolved over time from the design of chiral Lewis–Bronsted combined acid catalysts to the design of superacids to the design of biomimetic catalysts to the design of supramolecular acid-base combined catalysts. His current research is in developing catalytic, organic reactions and processes directed toward green & sustainable chemistry.
Photoinduced Assembly of C–N Bonds
Prof. Daniele LEONORI
UNIVERSITY OF MANCHESTER, Manchester, United Kingdom Read more
Prof. Daniele LEONORI
Daniele obtained his PhD at the University of Sheffield under the supervision of Professor Iain Coldham (2010). After postdoctoral studies with Professor Magnus Rueping (RWTH Aachen University) and with Professor Peter H. Seeberger (Max Planck Institute) he joined the group of Professor Varinder K. Aggarwal FRS as Research Officer (University of Bristol). In 2014 he commenced his independent career as Lecturer in Organic Chemistry at the University of Manchester and was promoted to Reader in 2018. The group’s main research interests are in the area of catalysis and synthetic chemistry, with a focus on the assembly of N-containing molecule. Daniele was awarded an EPSRC Early Career Fellowship in 2016, the ERC Starting Grant in 2017 and the RSC Harrison-Meldola Memorial Prize in 2018.
Ni-Catalyzed Functionalization of Remote sp3 C-H Bonds
Prof. Ruben MARTIN
INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA, Tarragona, Spain Read more
Prof. Ruben MARTIN
Ruben Martin was born in Barcelona in 1976. He received his Ph.D in 2003 at the Universitat de Barcelona with Prof. Antoni Riera, working on the total synthesis of glycosidases inhibitors.
In January 2004 he moved to the Max-Planck-Institut für Kohlenforschung as a Humboldt postdoctoral fellow with Prof. Alois Fürstner, where he worked on the application of novel iron catalysts for cross-coupling and Alder-ene type reactions.
In September 2008 he joined the ICIQ as a group leader. His current research interests concern the discovery and development of synthetically useful organometallic methodologies. Rubén Martín was promoted to Associate Professor in July 2013.In october 2013, he became ICREA (Catalan Institution of Research and Advanced Studies) Research Professor.
During his time at ICIQ, he has received the 2010 RSEQ Young Investigator Award, 2011 Thieme Chemistry Journal Award, 2011 Eli Lilly Young Research Investigator Award, 2015 RSEQ Excellent Research Award, 2011 ERC Starting Grant, 2017 Marcial Moreno Lectureship Award, 2017 OMCOS Award, 2017 Liebig-Lectureship Award, 2018 Pharmaron Lectureship Award, 2018 Bristol-Myers-Squibb Lectureship Award, 2018 Genentech Lectureship Award, 2018 ChemSocRev Pioneering Investigator Award, 2018 Hirata Award, 2018 IOCF Lectureship Award, 2018 Banc Sabadell Award to Sciences and Engineering, 2019 ParazaPharma Lectureship Award, 2019 Boehringer Ingelheim Award, 2019 MIT/Merck Lectureship Award, 2019 Novartis Chemistry Lectureship Award and 2020 Arthur C. Cope Scholar Award.
Shuttle Catalysis – A Conceptual Blueprint for Reversible Functional Group Transfer
Bill Morandi studied at the ETH Zurich from 2003–2012, earning a B.Sc. in Biology, a M.Sc. in Chemical Biology and a PhD in Organic Chemistry working with Prof. Erick M. Carreira. After a postdoc with Prof. Robert H. Grubbs at CalTech, he led an independent Max Planck Research Group from 2014–2018 at the Max-Planck-Institut für Kohlenforschung in Germany. Since July 2018, he has been an Associate Professor (with Tenure) at the ETH Zurich where he holds a chair in synthetic organic chemistry. His independent research program targets the development of new concepts in catalysis, with a particular emphasis on employing inexpensive and sustainable catalysts to transform broadly available feedstocks, such as polyols and hydrocarbons, into valuable building blocks for applications in medicine and materials science.
Harnessing the Chemistry of Plant Natural Product Biosynthesis
Prof. Sarah E. O’CONNOR
MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY, Jena, Germany Read more
Prof. Sarah E. O’CONNOR
Prof. Dr. Sarah Ellen O’Connor is Director of the Department of Natural Product Biosynthesis at the Max Planck Institute of Chemical Ecology (Jena, Germany). She obtained her PhD in Organic Chemistry from the Massachusetts Institute of Technology in 2001, and was an ACS Irving Sigal post-doctoral fellow at the Department of Biological Chemistry at Harvard Medical School (Boston, USA) from 2001-2003. From 2003-2011 she was Assistant and Associate Professor of Chemistry at the Massachusetts Institute of Technology, from 2011-2019 she was a Project Leader and Professor in the Department of Biological Chemistry at the John Innes Centre, and in 2019 she moved to the Max Planck Institute of Chemical Ecology. Her major research interest is plant biosynthetic pathways, where her group takes a multi-disciplinary approach to discover new genes responsible biosynthesis of complex natural products. Her group also studies the mechanism, engineering and evolution of these biosynthetic enzymes.
What's New with Simple Ambident Pro-nucleophiles
Prof. Jean RODRIGUEZ
AIX-MARSEILLE UNIVERSITY, Marseille, France Read more
Prof. Jean RODRIGUEZ
Jean Rodriguez was born in Cieza (Spain) in 1958, and in 1959 his family emigrated to France. He is currently Professor of organic chemistry at Aix-Marseille University (AMU) and director of the Institut des Sciences Moléculaires de Marseille (iSm2), a joint research unit (UMR) with the Centre National de la Recherche Scientifique (CNRS). After studying chemistry at AMU, he completed his Ph.D. starting in 1984 as a CNRS researcher with Prof. B. Waegell and Prof. P. Brun. He then moved to the University of California at Berkeley (US) to join the group of Prof. K. P. C. Vollhardt as a postdoctoral associate for one year. After completion of his Habilitation Diploma (HDR) from AMU in 1992 he was awarded the ACROS prize in Organic Chemistry in 1998, and in 2009 the prize of the Division of Organic Chemistry from the French Chemical Society. More recently, he was nominated “Distinguished member” of the French Chemical Society and became member of the Editorial Board of the European Journal of Organic Chemistry, both in 2013. The same year, he was chairman of the 18th European Symposium on Organic Chemistry for which he is a member of the Scientific International Board. His research interests include the development of multiple bond-forming transformations including domino and multicomponent reactions, with a recent focus on new enantioselective organocatalyzed transformations and multicalytic systems involving the reactivity of 1,2- and 1,3-dicarbonyl compounds.
Designer Enzymes for Unnatural Biocatalysis
Prof. Gerard ROELFES
UNIVERSITY OF GRONINGEN, Groningen, The Netherlands Read more
Prof. Gerard ROELFES
Gerard Roelfes is professor of Biomolecular Chemistry & Catalysis at the University of Groningen, the Netherlands. He obtained his MSc and PhD (2000) from the University of Groningen. His PhD research he carried out under supervision of Prof. Ben L. Feringa, in a joint project with the group of Prof. Lawrence Que Jr. (Univ. Minnesota), in whose lab he carried out part of the work. After his PhD he went for a post-doctoral stay with Prof. Donald Hilvert at the ETH-Zürich (Switzerland). In 2003 he returned to the University of Groningen as a junior research group leader. He became Assistant Professor in 2006, Associate Professor in 2010 and since 2015 is Full Professor. His research interests are enzyme design, bio-orthogonal catalysis and catalysis in living cells.
Title to be Announced
Prof. Corinna SCHINDLER
UNIVERSITY OF MICHIGAN, Ann Arbor, United States Read more
Complex Natural Products as a Driving Force for Discovery in Organic Chemistry
Prof. Brian STOLTZ
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, United States Read more
Prof. Brian STOLTZ
Brian M. Stoltz was born in Philadelphia, PA in 1970. After spending a year abroad at the Ludwig Maximilians Universität in München, Germany, he obtained his B.S. degree in Chemistry and B.A. degree in German from the Indiana University of Pennsylvania in Indiana, PA. Following graduate work at Yale University in the lab of John L. Wood and an NIH postdoctoral fellowship at Harvard in the Corey lab he took a position at the California Institute of Technology. A member of the Caltech faculty since 2000, he is currently Professor of Chemistry. His research interests lie in the development of new methods for general applications in synthetic chemistry and biologically active small molecules. Among his many distinctions, Professor Stoltz has been the recipient of the Arthur C. Cope Scholar and the E. J. Corey Awards from the American Chemical Society, the Presidential Early Career Award in Science and Engineering (PECASE) from the White House, the 2009 Raymond and Beverly Sackler Prize in the Physical Sciences for Chemistry, and was the 2015 recipient of the Mukaiyama Award by the Society of Synthetic Organic Chemistry, Japan. He was named the recipient of the 2018 American Chemical Society Award for Creative Work in Synthetic Organic Chemistry and in 2019 became a Fellow of the American Chemical Society. Professor Stoltz has trained more than 200 students and postdocs, who have gone on to successful independent careers in industry and academia. In 2017, he was awarded the Richard P. Feynman Prize for Excellence in Teaching at Caltech, the highest honor for teaching at the institute.
Studies ETH Zürich (1987-1992); Ph. D. ETH Zürich (1995, Supervisor: Prof. D. Seebach, asymmetric synthesis); Postdoc Pittsburgh Univ. (1995-1996, Supervisor: Prof. D. P. Curran, fluorous chemistry); Habilitation ETH Zürich (1996-2000, radical chemistry); Associate Prof. Marburg Univ. (2000-2004, radical chemistry in synthesis and in materials science); Full Prof. Münster Univ. (2004-present, radical chemistry, surface chemistry, catalysis).
Synthesis of Highly Strained Hydrocarbon Nanobelts
Mei-Xiang Wang graduated from Fudan University (1983). After spending 3 years in Beijing General Research Institute of Non-ferrous Metals as a research associ-ate, he joined Institute of Chemistry, Chinese Academy of Sciences (ICCAS) at Beijing and obtained his master degree (1989) and PhD (1992). He then worked at ICCAS ranking from assistant professor, associate professor to professor. He has joined Tsinghua University since the May of 2009. His research interests in-clude macrocyclic and supramolecular chemistry, anion- non-covalent bond in-teractions, high valent organocopper chemistry, catalytic asymmetric reactions of tertiary enamides, enantioselective biotransformations of nitriles and amides and their applications in the synthesis of natural products and bioactive compounds.
Strained Rings, Hypervalent Bonds, Tethers: Reactivity Design for Synthesis
Jérôme Waser studied chemistry at ETH Zurich, where he obtained his PhD degree in 2006 with Prof. Erick M. Carreira. In 2006, he joined Prof. Barry M. Trost at Stanford University as a SNF postdoctoral fellow. Since October 2007 he has been professor of organic chemistry at the Laboratory of Catalysis and Organic Synthesis (LCSO) at the Institute of Chemical Sciences and Engineering (ISIC) of the Ecole Polytechnique Fédérale de Lausanne (EPFL), where he was promoted full professor in 2019. His research group is focusing on the development of Umpolung strategies based on the use of heterocyclic hypervalent iodine reagents, the application of strained rings in synthetic chemistry and new tethering approaches for selective functionalization.
Reshaping Molecules with Reactive Heterocycles: from Cycloadditions for Odd-membered Carbocycles to New Organic Materials
Johan Winne is a tenure track ‘docent’ (assistant professor) at Ghent University since 2015. There, he leads an organic synthesis research group, consisting of chemists fascinated by terpene natural product families, modular heterocyclic building blocks, and cycloadditions. Next to these research lines, he also closely collaborates with research groups active in polymer chemistry, pharmacy and plant biology. Such collaborative efforts include the development of new dynamic covalent chemistries and click-type bioorthogonal reactions, useful for the functionalisation of (bio)macromolecules.
Johan Winne obtained his PhD at Ghent University in 2007, having worked on cationic polycyclisation cascades related to steroid and triterpenoid biosynthesis in the group of Pierre De Clercq. He also held a two-year position as postdoctoral research fellow at Nottingham University (UK) under the guidance of Gerry Pattenden, working on the total synthesis of terpenoid natural products. From 2009 until 2015 he held a combined teaching and research position as a ‘doctor-assistant’ in the department of Organic and Macromolecular Chemistry at Ghent University, the department he is still currently affilliated with as an independent faculty member.